NIHR BioResource for Translational Research in Common and Rare Diseases (NIHR BioResource)

The NIHR Exeter Clinical Research Facility (Exeter CRF) is one of 18 local recruitment centres for the national NIHR BioResource. The NIHR BioResource recruits patients with common or rare diseases and healthy volunteers who are willing to provide a DNA sample and information about their health, lifestyle and family history. Participants may then be contacted by the BioResource team for further research studies, based on the information obtained when they first registered. Over 250,000 people have already been recruited and up to 50,000 new participants will be recruited through the local centres each year. Each centre will recruit people with and without health conditions.

What’s involved?

You will be invited for an initial single appointment (approx. 30 minutes) here in the Exeter CRF at which you will be asked to provide a blood sample, we will measure your height, weight and blood pressure, and will ask you to complete a lifestyle/medical history questionnaire.

More information can be found here.

Specific BioResource Rare and Common Disease Cohorts

Working closely with clinical colleagues enables us to identify and recruit participants with a range of common and rare diseases (such as Inflammatory Bowel Disease and Monogenic Beta cell Diabetes), while our regular public outreach programmes help to identify the healthy volunteers, who are also needed.

Please see links below for more information on our specific Rare and Common Disease Cohorts or call 01392408181 or email crf@exeter.ac.uk

IBD BioResource – Inflammatory Bowel Disease

IMID BioResource – Immune Mediated Inflammatory Diseases

NAFLD BioResource – Non Alcoholic Fatty Liver Disease

Rare Disease BioResource Cohort: IAN – IgA Nephropathy

Rare Disease BioResource Cohort: SSC – Systemic Sclerosis

Rare Disease BioResource Cohort: IND – Rare Inherited Neurological Disorders

Using local Clinical Expertise, we have recently become the lead site for a new cohort of participants diagnosed with a rare type of diabetes called Monogenic Beta Cell Diabetes.

Rare Disease BioResource Cohort: MBD – Monogenic Betacell Diabetes

Later this year we will also be opening:-

Rare Disease BioResource Cohort: FIP – Familial Intestinal Pneumonia

Rare Disease BioResource Cohort: SHG – Severe Hyperemesis Gravidarium

Rare Disease BioResource Cohort: HCP – Intrahepatic Cholestasis of Pregnancy

We hope to expand recruitment to more rare disease cohorts as specific local clinical expertise is identified.