Health Category |
Publication |
DOI |
| Genetics | Edghill EL, Khamis A, Weedon MN, Walker M, Hitman GA, McCarthy MI, Owen KR, Ellard S, T Hattersley A, Frayling TM. Sequencing PDX1 (insulin promoter factor 1) in 1788 UK individuals found 5% had a low frequency coding variant, but these variants are not associated with Type 2 diabetes. Diabet Med. 2011 Jun;28(6):681-4 | DOI: 10.1111/j.1464-5491.2011.03269.x |
| Freathy RM, Kazeem GR, Morris RW, Johnson PC, Paternoster L, Ebrahim S, Hattersley AT, Hill A, Hingorani AD, Holst C, Jefferis BJ, Kring SI, Mooser V, Padmanabhan S, Preisig M, Ring SM, Sattar N, Upton MN, Vollenweider P, Waeber G, Sørensen TI, Frayling TM, Watt G, Lawlor DA, Whincup PH, Tozzi F, Davey Smith G, Munafò M. Genetic variation at CHRNA5-CHRNA3-CHRNB4 interacts with smoking status to influence body mass index. International Journal of Epidemiology. Dec 2011;40 (6):1617–1628 | doi.org/10.1093/ije/dyr077 | |
| Zhai GJ, Teumer A, Stolk L, Perry JRB, Vandenput L, Coviello AD, Koster A, Bell JT, Bhasin S, Eriksson J, Eriksson A, Ernst F, Ferrucci L, Frayling TM, Glass D, Grundberg E, Haring R, Hedman AK, Hofman A, Kiel DP, Kroemer HK, Liu YM, Lunetta KL, Maggio M, Lorentzon M, Mangino M, Melzer D, Miljkovic I, Nica A, Penninx BWJH, Vasan RS, Rivadeneira F, Small KS, Soranzo N, Uitterlinden AG, Volzke H, Wilson SG, Xi L, Zhuang WV, Harris TB, Murabito JM, Ohlsson C, Murray A, de Jong FH, Spector TD, Wallaschofski H, MuTHER Consortium. Eight Common Genetic Variants Associated with Serum DHEAS Levels Suggest a Key Role in Ageing Mechanisms. PLOS GENET. April 2011;7(4):e1002025 | doi.org/10.1371/journal.pgen.1002025 | |
| Harries LW, Hernandez D, Henley W, Wood AR, Holly AC, Bradley-Smith RM, Yaghootkar H, Dutta A, Murray A, Frayling TM, Guralnik JM, Bandinelli S, Singleton A, Ferrucci L, Melzer D. Human aging is characterized by focused changes in gene expression and deregulation of alternative splicing. Aging Cell. 2011;10(5),868-878 | doi: 10.1111/j.1474-9726.2011.00726.x | |
| Yang J, Weedon MN, Purcell S, Lettre G, Estrada K, Willer CJ, Smith AV, Ingelsson E, O’Connell JR, Mangino M, Magi R, Madden PA, Heath AC, Nyholt DR, Martin NG, Montgomery GW, Frayling TM, Hirschhorn JN, McCarthy MI, Goddard ME, Visscher PM, GIANT Consortium. Genomic inflation factors under polygenic inheritance. European Journal of Human Genetics 2011;19:807–812 | doi:10.1038/ejhg.2011.39 | |
| Wood AR, Hernandez DG, Nalls MA, Yaghootkar H, Gibbs JR, Harries LW, Chong S, Moore M, Weedon MN, Guralnik JM, Bandinelli S, Murray A, Ferrucci L, Singleton AB, Melzer D, Frayling TM. Allelic heterogeneity and more detailed analyses of known loci explain additional phenotypic variation and reveal complex patterns of association. Human Molecular Genetics. Oct 2011; 20(20):4082–4092 | doi.org/10.1093/hmg/ddr328 | |
| Nalls MA, Couper DJ, Tanaka T, van Rooij FJA, Chen MH, Smith AV, Toniolo D, Zakai NA, Yang Q, Greinacher A, Wood AR, Garcia M, Gasparini P, Liu Y, Lumley T, Folsom AR, Reiner AP, Gieger C, Lagou V, Felix JF, Volzke H, Gouskova NA, Biffi A, Doring A, Volker U, Chong S, Wiggins KL, Rendon A, Dehghan A, Moore M, Taylor K, Wilson JG, Lettre G, Hofman A, Bis JC, Pirastu N, Fox CS, Meisinger C, Sambrook J, Arepalli S, Nauck M, Prokisch H, Stephens J, Glazer NL, Cupples LA, Okada Y, Takahashi A, Kamatani Y, Matsuda K, Tsunoda T, Tanaka T, Kubo M, Nakamura Y, Yamamoto K, Kamatani N, Stumvoll M, Tonjes A, Prokopenko I, Illig T, Patel KV, Garner SF, Kuhnel B, Mangino M, Oostra BA, Thein SL, Coresh J, Wichmann HE, Menzel S, Lin JP, Pistis G, Uitterlinden AG, Spector TD, Teumer A, Eiriksdottir G, Gudnason V, Bandinelli S, Frayling TM,Chakravarti A, van Duijn CM, Melzer D, Ouwehand WH, Levy D, Boerwinkle E, Singleton AB, Hernandez DG, Longo DL, Soranzo N, Witteman JCM, Psaty BM, Ferrucci L, Harris TB, O’Donnell CJ, Ganesh SK. Multiple Loci Are Associated with White Blood Cell Phenotypes. PLOS GENET. June 2011;7(6): e1002113 | doi.org/10.1371/journal.pgen.1002113 | |
| Paternoster L, Howe LD, Tilling K, Weedon MN, Freathy RM, Frayling TM, Kemp JP, Smith GD, Timpson NJ, Ring SM, Evans DM, Lawlor DA. Adult height variants affect birth length and growth rate in children. Human Molecular Genetics. Oct 2011;20(20):4069–4075 | doi.org/10.1093/hmg/ddr309 | |
| Kooner JS, Saleheen D, Sim X, Sehmi J, Zhang WH, Frossard P, Been LF, Chia KS, Dimas AS, Hassanali N, Jafar T, Jowett JBM, Li XZ, Radha V, Rees SD, Takeuchi F, Young R, Aung T, Basit A, Chidambaram M, Das D, Grundberg E, Hedman AK, Hydrie ZI, Islam M, Khor CC, Kowlessur S, Kristensen MM, Liju S, Lim WY, Matthews DR, Liu JJ, Morris AP, Nica AC, Pinidiyapathirage JM, Prokopenko I, Rasheed A, Samuel M, Shah N, Shera AS, Small KS, Suo C, Wickremasinghe AR, Wong TY, Yang MY, Zhang F, Abecasis GR, Barnett AH, Caulfield M, Deloukas P, Frayling TM, Froguel P, Kato N, Katulanda P, Kelly MA, Liang JB, Mohan V, Sanghera DK, Scott J, Seielstad M, Zimmet PZ, Elliott P, Teo YY, McCarthy MI, Danesh J, Tai ES, Chambers JC, DIAGRAM, MuTHER. Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci. Nat Genet. Aug 2011;43(10):984-9 | doi: 10.1038/ng.921 | |
| Yaghootkar H, Hernandez D, Nalls M, Wood A, Gibbs R, Harries L, Chong S, Moore M, Guralnik J, Bandinell S, Murray A, Ferrucci L, Singleton A, Melzer D, Frayling T. Identifying likely causal connections between gene expression levels using a Mendelian randomization approach. Clinical Biochemistry. Sept 2011;44(13):S294 | DOI: 10.1016/j.clinbiochem.2011.08.739 | |
| Ehret GB, Munroe PB, Rice KM, Bochud M, Johnson AD, Chasman DI, Smith AV, Tobin MD, Verwoert GC, Hwang SJ, Pihur V, Vollenweider P, O’Reilly PF, Amin N, Bragg-Gresham JL, Teumer A, Glazer NL, Launer L, Zhao JH, Aulchenko Y, Heath S, Sober S, Parsa A, Luan JA, Arora P, Dehghan A, Zhang F, Lucas G, Hicks AA, Jackson AU, Peden JF, Tanaka T, Wild SH, Rudan I, Igl W, Milaneschi Y, Parker AN, Fava C, Chambers JC, Fox ER, Kumari M, Go MJ, van der Harst P, Kao WHL, Sjogren M, Vinay DG, Alexander M, Tabara Y, Shaw-Hawkins S, Whincup PH, Liu YM, Shi G, Kuusisto J, Tayo B, Seielstad M, Sim X, Nguyen KDH, Lehtimaki T, Matullo G, Wu Y, Gaunt TR, Onland-Moret NC, Cooper MN, Platou CGP, Org E, Hardy R, Dahgam S, Palmen J, Vitart V, Braund PS, Kuznetsova T, Uiterwaal CSPM, Adeyemo A, Palmas W, Campbell H, Ludwig B, Tomaszewski M, Tzoulaki I, Palmer ND, Aspelund T, Garcia M, Chang YPC, O’Connell JR, Steinle NI, Grobbee DE, Arking DE, Kardia SL, Morrison AC, Hernandez D, Najjar S, McArdle WL, Hadley D, Brown MJ, Connell JM, Hingorani AD, Day INM, Lawlor DA, Beilby JP, Lawrence RW, Clarke R, Hopewell JC, Ongen H, Dreisbach AW, Li YL, Young JH, Bis JC, Kahonen M, Viikari J, Adair LS, Lee NR, Chen MH, Olden M, Pattaro C, Bolton JAH, Kottgen A, Bergmann S, Mooser V, Chaturvedi N, Frayling TM, Islam M, Jafar TH, Erdmann J, Kulkarni SR, Bornstein SR, Grassler J, Groop L, Voight BF, Kettunen J, Howard P, Taylor A, Guarrera S, Ricceri F, Emilsson V, Plump A, Barroso IS, Khaw KT, Weder AB, Hunt SC, Sun YV, Bergman RN, Collins FS, Bonnycastle LL, Scott LJ, Stringham HM, Peltonen L, Perola M, Vartiainen E, Brand SM, Staessen JA, Wang TJ, Burton PR, Artigas MS, Dong YB, Snieder H, Wang XL, Zhu HD, Lohman KK, Rudock ME, Heckbert SR, Smith NL, Wiggins KL, Doumatey A, Shriner D, Veldre G, Viigimaa M, Kinra S, Prabhakaran D, Tripathy V, Langefeld CD, Rosengren A, Thelle DS, Corsi AM, Singleton A, Forrester T, Hilton G, McKenzie CA, Salako T, Iwai N, Kita Y, Ogihara T, Ohkubo T, Okamura T, Ueshima H, Umemura S, Eyheramendy S, Meitinger T, Wichmann HE, Cho YS, Kim HL, Lee JY, Scott J, Sehmi JS, Zhang WH, Hedblad B, Nilsson P, Smith GD, Wong A, Narisu N, Stancakova A, Raffel LJ, Yao J, Kathiresan S, O’Donnell CJ, Schwartz SM, Ikram MA, Longstreth WT, Mosley TH, Seshadri S, Shrine NRG, Wain LV, Morken MA, Swift AJ, Laitinen J, Prokopenko I, Zitting P, Cooper JA, Humphries SE, Danesh J, Rasheed A, Goel A, Hamsten A, Watkins H, Bakker SJL, van Gilst WH, Janipalli CS, Mani KR, Yajnik CS, Hofman A, Mattace-Raso FUS, Oostra BA, Demirkan A, Isaacs A, Rivadeneira F, Lakatta EG, Orru M, Scuteri A, Ala-Korpela M, Kangas AJ, Lyytikainen LP, Soininen P, Tukiainen T, Wurtz P, Ong RTH, Dorr M, Kroemer HK, Volker U, Volzke H, Galan P, Hercberg S, Lathrop M, Zelenika D, Deloukas P, Mangino M, Spector TD, Zhai GJ, Meschia JF, Nalls MA, Sharma P, Terzic J, Kumar MVK, Denniff M, Zukowska-Szczechowska E, Wagenknecht LE, Fowkes FGR, Charchar FJ, Schwarz PEH, Hayward C, Guo XQ, Rotimi C, Bots ML, Brand E, Samani NJ, Polasek O, Talmud PJ, Nyberg F, Kuh D, Laan M, Hveem K, Palmer LJ, van der Schouw YT, Casas JP, Mohlke KL, Vineis P, Raitakari O, Ganesh SK, Wong TY, Tai ES, Cooper RS, Laakso M, Rao DC, Harris TB, Morris RW, Dominiczak AF, Kivimaki M, Marmot MG, Miki T, Saleheen D, Chandak GR, Coresh J, Navis G, Salomaa V, Han BG, Zhu XF, Kooner JS, Melander O, Ridker PM, Bandinelli S, Gyllensten UB, Wright AF, Wilson JF, Ferrucci L, Farrall M, Tuomilehto J, Pramstaller PP, Elosua R, Soranzo N, Sijbrands EJG, Altshuler D, Loos RJF, Shuldiner AR, Gieger C, Meneton P, Uitterlinden AG, Wareham NJ, Gudnason V, Rotter JI, Rettig R, Uda M, Strachan DP, Witteman JCM, Hartikainen AL, Beckmann JS, Boerwinkle E, Vasan RS, Boehnke M, Larson MG, Jarvelin MR, Psaty BM, Abecasis GR, Chakravarti A, Elliott P, van Duijn CM, Newton-Cheh C, Levy D, Caulfield MJ, Johnson T, Int Consortium Blood Pressure Geno, CARDIoGRAM Consortium, CKDGen Consortium, KidneyGen Consortium, EchoGen Consortium, CHARGE-HF Consortium. Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature. Sept 2011;478(7367):103-9 | doi: 10.1038/nature10405 | |
| Strawbridge RJ, Dupuis J, Prokopenko I, Barker A, Ahlqvist E, Rybin D, Petrie JR, Travers ME, Bouatia-Naji N, Dimas AS, Nica A, Wheeler E, Chen H, Voight BF, Taneera J, Kanoni S, Peden JF, Turrini F, Gustafsson S, Zabena C, Almgren P, Barker DJP, Barnes D, Dennison EM, Eriksson JG, Eriksson P, Eury E, Folkersen L, Fox CS, Frayling TM, Goel A, Gu HF, Horikoshi M, Isomaa B, Jackson AU, Jameson KA, Kajantie E, Kerr-Conte J, Kuulasmaa T, Kuusisto J, Loos RJF, Luan JA, Makrilakis K, Manning AK, Martinez-Larrad MT, Narisu N, Mannila MN, Ohrvik J, Osmond C, Pascoe L, Payne F, Sayer AA, Sennblad B, Silveira A, Stancakova A, Stirrups K, Swift AJ, Syvanen AC, Tuomi T, van ‘t Hooft FM, Walker M, Weedon MN, Xie WJ, Zethelius B, Ongen H, Malarstig A, Hopewell JC, Saleheen D, Chambers J, Parish S, Danesh J, Kooner J, Ostenson CG, Lind L, Cooper CC, Serrano-Rios M, Ferrannini E, Forsen TJ, Clarke R, Franzosi MG, Seedorf U, Watkins H, Froguel P, Johnson P, Deloukas P, Collins FS, Laakso M, Dermitzakis ET, Boehnke M, McCarthy MI, Wareham NJ, Groop L, Pattou F, Gloyn AL, Dedoussis GV, Lyssenko V, Meigs JB, Barroso I, Watanabe RM, Ingelsson E, Langenberg C, Hamsten A, Florez JC, DIAGRAM Consortium, GIANT Consortium, MuTHER Consortium, CARDIoGRAM Consortium, C4D Consortium. Genome-Wide Association Identifies Nine Common Variants Associated With Fasting Proinsulin Levels and Provides New Insights Into the Pathophysiology of Type 2 Diabetes. Diabetes. Oct 2011;60(10): 2624-2634 | doi.org/10.2337/db11-0415 | |
| Chan YL, Holmen OL, Dauber A, Vatten L, Havulinna AS, Skorpen F, Kvaloy K, Silander K, Nguyen TT, Willer C, Boehnke M, Perola M, Palotie A, Salomaa V, Hveem K, Frayling TM, Hirschhorn JN, Weedon MN. Common Variants Show Predicted Polygenic Effects on Height in the Tails of the Distribution, Except in Extremely Short Individuals. PLOS GENET. Dec 2011;7(12):e1002439 | doi.org/10.1371/journal.pgen.1002439 | |
| Winney B, Boumertit A, Day T, Davison D, Echeta C, Evseeva I, Hutnik K, Leslie S, Nicodemus K, Royrvik EC, Tonks S, Yang XF, Cheshire J, Longley P, Mateos P, Groom A, Relton C, Bishop DT, Black K, Northwood E, Parkinson L, Frayling TM, Steele A, Sampson JR, King T, Dixon R, Middleton D, Jennings B, Bowden R, Donnelly P, Bodmer W. People of the British Isles: preliminary analysis of genotypes and surnames in a UK-control population. European Journal of Human Genetics. 2012;20:203–210 | doi:10.1038/ejhg.2011.127 | |
| Yang J, Ferreira T, Morris AP, Medland SE, Madden PAF, Heath AC, Martin NG, Montgomery GW, Weedon MN, Loos RJ, Frayling TM, McCarthy MI, Hirschhorn JN, Goddard ME, Visscher PM. Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits. Nature Genetics. March 2012;44(4):369-75, S1-3 | doi: 10.1038/ng.2213 | |
| Boraska V, Day-Williams A, Franklin CS, Elliott KS, Panoutsopoulou K, Tachmazidou I, Albrecht E, Bandinelli S, Beilin LJ, Bochud M, Cadby G, Ernst F, Evans DM, Hayward C, Hicks AA, Huffman J, Huth C, James AL, Klopp N, Kolcic I, Kutalik Z, Lawlor DA, Musk AW, Pehlic M, Pennell CE, Perry JRB, Peters A, Polasek O, Pourcain BS, Ring SM, Salvi E, Schipf S, Staessen JA, Teumer A, Timpson N, Vitart V, Warrington NM, Yaghootkar H, Zemunik T, Zgaga L, An P, Anttila V, Borecki IB, Holmen J, Ntalla I, Palotie A, Pietiläinen KH, Wedenoja J, Winsvold BS, Dedoussis GV, Kaprio J, Province MA, Zwart J-A, Burnier M, Campbell H, Cusi D, Davey Smith G, Frayling TM, Gieger C, Palmer LJ, Pramstaller PP, Rudan I, Völzke H, Wichmann H-E, Wright AF, Zeggini E. Genome-wide association study to identify common variants associated with brachial circumference: A meta-analysis of 14 cohorts. PLoS ONE. March 2012;7(3):e31369 | doi.org/10.1371/journal.pone.0031369 | |
| Dastani Z, Hivert M-F, Timpson N, Perry JRB, Yuan X, Scott RA, Henneman P, Heid IM, Kizer JR, Lyytikäinen L-P, Fuchsberger C, Tanaka T, Morris AP, Small K, Isaacs A, Beekman M, Coassin S, Lohman K, Qi L, Kanoni S, Pankow JS, Uh H-W, Wu Y, Bidulescu A, Rasmussen-Torvik LJ, Greenwood CMT, Ladouceur M, Grimsby J, Manning AK, Liu C-T, Kooner J, Mooser VE, Vollenweider P, Kapur KA, Chambers J, Wareham NJ, Langenberg C, Frants R, Willems-vanDijk K, Oostra BA, Willems SM, Lamina C, Winkler TW, Psaty BM, Tracy RP, Brody J, Chen I, Viikari J, Kähönen M, Pramstaller PP, Evans DM, Pourcain B, Sattar N, Wood AR, Bandinelli S, Carlson OD, Egan JM, Böhringer S, van Heemst D, Kedenko L, Kristiansson K, Nuotio M-L, Loo B-M, Harris T, Garcia M, Kanaya A, Haun M, Klopp N, Wichmann H-E, Deloukas P, Katsareli E, Couper DJ, Duncan BB, Kloppenburg M, Adair LS, Borja JB, Wilson JG, Musani S, Guo X, Johnson T, Semple R, Teslovich TM, Allison MA, Redline S, Buxbaum SG, Mohlke KL, Meulenbelt I, Ballantyne CM, Dedoussis GV, Hu FB, Liu Y, Paulweber B, Spector TD, Slagboom PE, Ferrucci L, Jula A, Perola M, Raitakari O, Florez JC, Salomaa V, Eriksson JG, Frayling TM, Hicks AA, Lehtimäki T, Da Smith G, Siscovick DS, Kronenberg F, van Duijn C, Loos RJF, Waterworth DM, Meigs JB, Dupuis J, Richards JB. Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: A multi-ethnic meta-analysis of 45,891 individuals. PLOS Genetics. 2012;8(3):e1002607 | doi.org/10.1371/journal.pgen.1002607 | |
| Yang J, Ferreira T, Morris AP, Medland SE, Madden PAF, Heath AC, Martin NG, Montgomery GW, Weedon MN, Loos RJ, Frayling TM, McCarthy MI, Hirschhorn JN, Goddard ME, Visscher PM. Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits. Nat Genet. March 2012;44(4):369-75, S1-3 | doi: 10.1038/ng.2213 | |
| Taal HR, St Pourcain B, Thiering E, Das S, Mook-Kanamori DO, Warrington NM, Kaakinen M, Kreiner-Møller E, Bradfield JP, Freathy RM, Geller F, Guxens M, Cousminer DL, Kerkhof M, Timpson NJ, Ikram MA, Beilin LJ, Bønnelykke K, Buxton JL, Charoen P, Chawes BLK, Eriksson J, Evans DM, Hofman A, Kemp JP, Kim CE, Klopp N, Lahti J, Lye SJ, McMahon G, Mentch FD, Müller-Nurasyid M, O’Reilly PF, Prokopenko I, Rivadeneira F, Steegers EAP, Sunyer J, Tiesler C, Yaghootkar H, Ikram MA, Fornage M, Smith AV, Seshadri S, Schmidt R, Debette S, Vrooman HA, Sigurdsson S, Ropele S, Coker LH, Longstreth Jr WT, Niessen WJ, DeStefano AL, Beiser A, Zijdenbos AP, Struchalin M, Jack Jr CR, Nalls MA, Au R, Hofman A, Gudnason H, van der Lugt A, Harris TB, Meeks WM, Vernooij MW, van Buchem MA, Catellier D, Gudnason V, Windham BG, Wolf PA, van Duijn CM, Mosley Jr TH, Schmidt H, Launer LJ, Breteler MMB, DeCarli C, Breteler MMB, Debette S, Fornage M, Gudnason V, Launer LJ, van der Lugt A, Mosley Jr TH, Seshadri S, Smith AV, Vernooij MW, Ang W, van Beijsterveldt T, Bergen N, Benke K, Berry D, Bradfield JP, Charoen P, Coin L, Cousminer DL, Das S, Elliott P, Evans DM, Frayling T, Freathy RM, Gaillard R, Groen-Blokhuis M, Guxens M, Hadley D, Hottenga JJ, Huikari V, Hypponen E, Kaakinen M, Kowgier M, Lawlor DA, Lewin A, Lindgren C, Marsh J, Middeldorp C, Millwood I, Mook-Kanamori DO, Nivard M, O’Reilly PF, Palmer LJ, Prokopenko I, Rodriguez A, Sebert S, Sovio U, St Pourcain B, Standl M, Strachan DP, Sunyer J, Taal HR, Thiering E, Tiesler C, Uitterlinden AG, Valcárcel B, Warrington NM, White S, Willemsen G, Yaghootkar H, Boomsma DI, Estivill X, Grant SFA, Hakonarson H, Hattersley AT, Heinrich J, Jaddoe VWV, Jarvelin M-R, McCarthy MI, Pennell CE, Power C, Timpson NJ, Widen E, Blakemore AIF, Chiavacci RM, Feenstra B, Fernandez-Banet J, Grant SFA, Hartikainen A-L, van der Heijden AJ, Iñiguez C, Lathrop M, McArdle WL, Mølgaard A, Newnham JP, Palmer LJ, Palotie A, Pouta A, Ring SM, Sovio U, Standl M, Uitterlinden AG, Wichmann H-E, Vissing NH, DeCarli C, van Duijn CM, McCarthy MI, Koppelman GH, Estivill X, Hattersley AT, Melbye M, Bisgaard H, Pennell CE, Widen E, Hakonarson H, Smith GD, Heinrich J, Jarvelin M-R, Jaddoe VWV, Adair LS, Ang W, Atalay M, van Beijsterveldt T, Bergen N, Benke K, Berry D, Bradfield JP, Charoen P, Coin L, Cousminer DL, Das S, Davis OSP, Elliott P, Evans DM, Feenstra B, Flexeder C, Frayling T, Freathy RM, Gaillard R, Geller F, Groen-Blokhuis M, Goh L-K, Guxens M, Haworth CMA, Hadley D, Hedebrand J, Hinney A, Hirschhorn JN, Holloway JW, Holst C, Hottenga JJ, Horikoshi M, Huikari V, Hypponen E, Iñiguez C, Kaakinen M, Kilpeläinen TO, Kirin M, Kowgier M, Lakka H-M, Lange LA, Lawlor DA, Lehtimäki T, Lewin A, Lindgren C, Lindi V, Maggi R, Marsh J, Middeldorp C, Millwood I, Mook-Kanamori DO, Murray JC, Nivard M, Nohr EA, Ntalla I, Oken E, O’Reilly PF, Palmer LJ, Panoutsopoulou K, Pararajasingham J, Prokopenko I, Rodriguez A, Salem RM, Sebert S, Siitonen N, Sovio U, St Pourcain B, Strachan DP, Sunyer J, Taal HR, Teo Y-Y, Thiering E, Tiesler C, Uitterlinden AG, Valcárcel B, Warrington NM, White S, Willemsen G, Yaghootkar H, Zeggini E, Boomsma DI, Cooper C, Estivill X, Gillman M, Grant SFA, Hakonarson H, Hattersley AT, Heinrich J, Hocher B, Jaddoe VWV, Jarvelin M-R, Lakka TA, McCarthy MI, Melbye M, Mohlke KL, Dedoussis GV, Ong KK, Pearson ER, Pennell CE, Price TS, Power C, Raitakari OT, Saw S-M, Scherag A, Simell O, Sørensen TIA, Timpson NJ, Widen E, Wilson JF. Common variants at 12q15 and 12q24 are associated with infant head circumference. Nature Genetics. 2012;44:532–538 | doi:10.1038/ng.2238 | |
| Ikram MA, Fornage M, Smith AV, Seshadri S, Schmidt R, Debette S, Vrooman HA, Sigurdsson S, Ropele S, Taal HR, Mook-Kanamori DO, Coker LH, Longstreth Jr WT, Niessen WJ, DeStefano AL, Beiser A, Zijdenbos AP, Struchalin M, Jack Jr CR, Rivadeneira F, Uitterlinden AG, Knopman DS, Hartikainen A-L, Pennell CE, Thiering E, Steegers EAP, Hakonarson H, Heinrich J, Palmer LJ, Jarvelin M-R, McCarthy MI, Grant SFA, Pourcain BS, Timpson NJ, Smith GD, Sovio U, Nalls MA, Au R, Hofman A, Gudnason H, van der Lugt A, Harris TB, Meeks WM, Vernooij MW, van Buchem MA, Catellier D, Jaddoe VWV, Gudnason V, Windham BG, Wolf PA, van Duijn CM, Mosley Jr TH, Schmidt H, Launer LJ, Breteler MMB, DeCarli C, Adair LS, Ang W, Atalay M, van Beijsterveldt T, Bergen N, Benke K, Berry D, Coin L, Davis OSP, Elliott P, Flexeder C, Frayling T, Gaillard R, Groen-Blokhuis M, Goh L-K, Haworth CMA, Hadley D, Hedebrand J, Hinney A, Hirschhorn JN, Holloway JW, Holst C, Jan Hottenga J, Horikoshi M, Huikari V, Hypponen E, Kilpeläinen TO, Kirin M, Kowgier M, Lakka H-M, Lange LA, Lawlor DA, Lehtimäki T, Lewin A, Lindgren C, Lindi V, Maggi R, Marsh J, Middeldorp C, Millwood I, Murray JC, Nivard M, Nohr EA, Ntalla I, Oken E, Panoutsopoulou K, Pararajasingham J, Rodriguez A, Salem RM, Sebert S, Siitonen N, Strachan DP, Teo Y-Y, Valcárcel B, Willemsen G, Zeggini E, Boomsma DI, Cooper C, Gillman M, Hocher B, Lakka TA, Mohlke KL, Dedoussis GV, Ong KK, Pearson ER, Price TS, Power C, Raitakari OT, Saw S-M, Scherag A, Simell O, Sørensen TIA, Wilson JF. Common variants at 6q22 and 17q21 are associated with intracranial volume. Nature Genetic. April 2012;44(5):539-44 | doi: 10.1038/ng.2245 | |
| Islam M, Jafar TH, Wood AR, De Silva NMG, Caulfield M, Chaturvedi N, Frayling TM. Multiple genetic variants explain measurable variance in type 2 diabetes-related traits in Pakistanis. Diabetologia. Aug 2012;55(8):2193-20 | doi: 10.1007/s00125-012-2560-y | |
| Metabolic and Endocrine | Taylor PN, Panicker V, Sayers A, Shields B, Iqbal A, Bremner AP, Beilby JP, Leedman PJ, Hattersley AT, Vaidya B, Frayling T, Evans J, Tobias JH, Timpson NJ, Walsh JP, Dayan CM. A meta-analysis of the associations between common variation in the PDE8B gene and thyroid hormone parameters, including assessment of longitudinal stability of associations over time and effect of thyroid hormone replacement. Eur J Endocrinol. 2011;164(5):773-780 | doi.org/10.1530/EJE-10-0938 |
Clinical Research Facility: Exeter
